MnDNA
Prevents skin ageing, improves skin complexion and epidermal renewalManganese carried by Highly Polymerized DNA
INCI Name Manganese DNA
Trade Name MnDNA
ORIGIN
NATURAL AND MARINE ORIGIN
Extracted from salmon milt in strict conditions in order to preserve the properties of this fundamental polymer.
ASPECT
White to cream-white fibers, measuring several cm long.
SOLUBILITY
Fibers are relatively soluble in water, forming a gel at low concentrations (1.0 to 3.0 %).
Insoluble in alcohol, acetone, ether and other organic solvents.
TYPICAL ANALYSIS
Nitrogen, Phosphorous, Deoxyribose, Manganese.
OBLIGATORY PARAMETERS OF QUALITY
• Equality of nucleic bases: (A/T), (G/C), [(A+G)/(T+C)] ratios about 1,
• High degree of polymerization by Size Exclusion Chromatography and Light Scattering Detector.
• UV absorption, hyperchromicity: 30.0 to 50.0 %.
BIOLOGICAL PROPERTIES*
• MnDNA is well known as a free radical scavenger (°OH radical)
• An electron spin resonance, ESR, study of DNA to scavenge hydroxyl radical (°OH) was carried out as the identification of 8 OH-deoxyguanosine resulting from °OH addition on DNA.
• Mitochondrial Super Oxyde Dismutase cofactor
• Blood capillary action
• Promote keratinocytes proliferation and collagen production.
COSMETIC USES
• Anti ageing products
• Complexion products
• Anti aggression products
• Skin renewal products
TYPICAL CONCENTRATION
0.25 to 1.0 % (w/v) in creams or 2.0 to 3.0 % in aqueous gels.
*Studies or bibliography to be provided upon request
